Allergies are protective reactions by the immune system towards certain foreign substances in the body. At present, this disease is considered to be one of the most widespread. Since so many people suffer from allergies, they are considered a global medical problem.
Allergic symptoms develop in response to contact with an allergen. Allergens can include plant pollen, dust, and many others. They are usually microscopic and thus can enter the patient’s body via skin, eyes, airways, and food.
Patients can be allergic to a wide variety of substances, such as chocolate, nuts, or cheese, which are known as food allergies. Other common allergens include house dust, tree and plant pollen, fungal spores, wool particles, and animal or bird dander. These allergens are inhaled from the air.
Plant pollen and spores tend to cause seasonal allergies. The intensity of the allergic reaction depends on the concentration of pollen in the air. Pollen and spores from many trees and plants are microscopic compared to those of fruit trees pollinated by insects, and in sunny weather, winds can carry these allergens for miles. The higher the concentration of pollen in the air, the more patients suffer from intense allergic reactions.
The type of allergy is defined by the disease symptoms and intensity. Allergic reactions can range from slight to life-threatening and include the following:
- Respiratory symptoms, including sneezing, rhinitis, and coughing with sputum discharge.
- Tearing and redness of the eyelids and sclera.
- Burning in the eye area.
- Itching in the nasal area.
- Rashes on the skin and mucous membranes.
- Itching and scaling of the skin.
- Dyspepsia, including nausea, vomiting, and diarrhea.
Prednisone requires a prescription from a doctor and is an effective remedy for allergies. It is indicated for severe allergic reactions. It is advantageous in that it has few side effects with a short-term course of treatment.
For example, in cases of severe bronchial asthma, prednisone quickly resolves the allergic reaction and restores normal breathing. This is also true for skin diseases caused by allergic reactions, including congenital allergic dermatitis in children and eczema in adults.
Prednisone is not typically prescribed for pollinosis and year-round allergic rhinitis. However, when the disease is severe and carries a threat of developing further allergic processes, short-term administration of this drug can help to remove or reduce this risk.
One-time use of prednisone, even in high doses, typically does not cause side effects or lead to an overdose. The treatment course and drug dosage depend on the patient’s condition, disease stage, and individual tolerance of the drug, as well as the selected therapy’s effectiveness.
During acute stages of the disease, adults on replacement therapy are recommended to take an initial daily dose of 20 mg. For a patient receiving regular treatment, a daily dose can be up to 10 mg. For children, the initial dosage is calculated as 12 mg per kg of body weight, administered 4 to 6 times daily. Once the therapeutic effect is achieved, the dose should be reduced gradually over 3-5 days. Abruptly discontinuing the treatment can be dangerous.
Prednisone effectively treats anaphylactic shock because it activates adrenaline production in the body. In addition, the drug inhibits immune bodies from accumulating in the affected area, suppressing phagocytosis and cell enzymes.
It also helps to reduce the intensity of the inflammatory process. However, patients should not take prednisone if they have following contraindications:
- An allergy to the drug or its components.
- Vaccination or active form of tuberculosis.
- Viral diseases or generalized mycosis.
- An acute stage peptic ulcer or erosive gastritis.
- Herpes, diabetes, or insufficient kidney function.
- Severe arterial hypertension.
- Predisposition to thromboembolism.
It should be noted that during pregnancy, prednisone should be used with caution, as it can penetrate the placenta and affect the fetus.