Prednisone is usually prescribed at a dose of 4-6 5mg tablets per day. The maintenance dose is 1-2 5mg tablets per day. For the treatment of diseases, such as nephrosis-kidney disease and some rheumatic diseases, prednisone is prescribed in higher doses. Treatment should be stopped slowly, gradually reducing the dose. The dose for children is usually 1-2 mg per kg of body weight per day.
Like all medicines, prednisone has side effects. Despite its effectiveness, the possible harm limits its use in the treatment of certain diseases. In a short course of therapy, potential side effects do not have time to cause destructive consequences and disappear after treatment.
With prolonged therapy, there can be complex problems. This hormonal drug may cause an addiction effect. During long-term treatment, ions of potassium and nitrogen are rapidly removed, sodium and water accumulate, blood sugar levels rise, and the patient gains weight. In addition, the functioning of the endocrine glands is disrupted, and the work of the adrenal glands is inhibited, which is why treatment with prednisone can disrupt women’s menstrual cycles and slow growth in children.
Therefore, during therapy, it is often necessary to perform a bone marrow examination using X-rays. Long-term use of the drug can affect the muscle tissue. If there are such symptoms, you should stop taking prednisone and replace it with a similar medicine.
The side effects of the drug on other organs:
- hypertension development.
- increased acidity, inability to process dairy food.
- risk of blood clots due to high blood density.
- violation of the adrenal glands.
- depression, euphoria.
Pednisone in drops (for the treatment of eye diseases) can cause dryness in the eyes, and can also lead to changes in corneal density, as well as nerve damage.
Prednisone in the form of an ointment can cause:
- increased dryness.
- stretch marks.
Before you start treatment with this drug, you need to know all the possible consequences and side effects.
If prednisone is prescribed for a long period (a full course of therapy can last 6-12 months), additional medications should be prescribed to prevent the side effects of prednisone.
To protect the mucous membrane of the upper gastrointestinal tract, patients should take antacid medicines, H+ pump blockers, and drugs that improve the motility of the gastrointestinal tract. All doses of drugs are selected individually by age and body weight requirements.
The long-term use of steroids can cause a decrease in the mass of bone tissue, which eventually leads to fractures of the bones. This condition can also be prevented by taking Vitamin D with calcium. The dosage of the drugs is also selected individually.
What else is necessary should be considered?
Compulsory monitoring of blood pressure
Observation by an ophthalmologist: vision control, the state of intraocular pressure, and the lens of the eye.
Checking the patient’s blood glucose level.
The state of the patient’s mental health.
Keeping track of the patient’s weight and diet.